Constituents of Schisandra verruculosa and Their Cytotoxic Effect on Human Cancer Cell Lines
نویسندگان
چکیده
1,2-bis-(4-Hydroxy-3-methoxyphenyl)-3-hydroxypropan1-one (evafolin B, 1), 1-(4-hydroxy-3-methoxyphenyl)3-hydroxypropan-1-one (2), were isolated for the first time from the genus Schisandra, along with abscisic acid (3), 4-hydroxybenzaldehyde (4), 4-hydroxybenzoic acid (5), methyl 4-hydroxybenzoate (6), methyl 3,4-dihydroxybenzoate (7), and vanillic acid (8). All the compounds were evaluated for their antitumor, antiproliferative, and antioxidant activities. Only compound 7 exhibited moderate activity against three human cancer cell lines and human lymphocytic proliferation, as well as strong inhibitory activity for DPPH free radicals, only slightly less than ascorbic acid.
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